Spirituality is a travelling concept among different disciplines. As for psychology, spirituality has long been a neglected topic – especially in the academic context. However, during the last decade there has been an increase of theoretical and empirical work, mainly emerging from positive and life-span developmental psychology. This research focuses spirituality either as an element of well-being or as predictor of well-being and health (e.g. as a coping strategy), or finally as an outcome after dealing with critical life events (i.e. spiritual growth). This knowledge has an impact on spiritual care – and vice-versa spiritual care – as a growing inter- and transdisciplinary field – has an impact on clinical psychological practice. Against this background the aims of the present contribution are: - To provide some empirical data on spiritual and religious practice in Switzerland (Swiss Social Report 2012). - To shed light on the importance of spirituality in times of incertitude, namely critical life events (such as divorce and bereavement), and two biographical transitions, the transition into the second life half (midlife transition), and the transition to very old age.