Association of early- and adult-life socioeconomic circumstances with muscle strength in older age
|Title||Association of early- and adult-life socioeconomic circumstances with muscle strength in older age|
|Publication Type||Journal Article|
|Year of Publication||2018|
|Authors||Cheval, B, Boisgontier, M, Orsholits, D, Sieber, S, Guessous, I, Gabriel, R, Stringhini, S, Blane, D, Van der Linden, BWA, Kliegel, M, Burton-Jeangros, C, Courvoisier, D, Cullati, S|
|Journal||Age and Ageing|
|Keywords||ageing, hand strength, health, older people, socioeconomic status|
Background: socioeconomic circumstances (SEC) during a person’s lifespan influence a wide range of health outcomes. However, solid evidence of the association of early- and adult-life SEC with health trajectories in ageing is still lacking. This study assessed whether early-life SEC are associated with muscle strength in later life—a biomarker of health—and whether this relationship is caused by adult-life SEC and health behaviours. Methods: we used data from the Survey of Health Ageing and Retirement in Europe, a 12-year population-based cohort study with repeated measurement in six waves (2004–15) and retrospective collection of life-course data. Participants’ grip strength was assessed by using a handheld dynamometer. Confounder-adjusted logistic mixed-effect models were used to examine the associations of early- and adult-life SEC with the risk of low muscle strength (LMS) in older age. Results: a total of 24,179 participants (96,375 observations) aged 50–96 living in 14 European countries were included in the analyses. Risk of LMS was increased with disadvantaged relative to advantaged early-life SEC. The association between risk of LMS and disadvantaged early-life SEC gradually decreased when adjusting for adult-life SEC for both sexes and with unhealthy behaviours for women. After adjusting for these factors, all associations between risk of LMS and early-life SEC remained significant for women. Conclusion: early-life SEC are associated with muscle strength after adjusting for adult-life SEC and behavioural lifestyle factors, especially in women, which suggests that early life may represent a sensitive period for future health.